A methyl binding domain in complex with DNA bearing a symmetrically methylated CpG site. Methylation of cytosines in this sequence context in gene promoters leads to reduced expression of certain proteins in many cancers.
| Redox Biology
Reversible, genetically encoded sensors of hydrogen peroxide allow visualization and quantification of this oxidant in time and space.
Polymerization-based amplification transduces molecular recognition
events into micron-scale hydrogel
films that are visible by eye. These reactions proceed in air within thirty-five to one hundred seconds.