Senior Laboratory Technologist
Research
Rapid UTI Beta-Lactamase Identification (RUβI) Test.
The rise of antimicrobial resistance (AMR), particularly due to beta-lactamase-producing bacteria, poses a significant threat to global health by compromising the efficacy of beta-lactam antibiotics. We are working on a diagnostic test that offers a rapid and accurate method to identify beta-lactamase enzymes in bacterial infections. By quickly detecting the presence and type of beta-lactamases, this test enables targeted antibiotic therapy, reducing the misuse of broad-spectrum antibiotics and minimizing the selection pressure that drives resistance. The implementation of this diagnostic tool in clinical settings can enhance treatment outcomes, preserve the effectiveness of existing antibiotics and play a critical role in the global effort to combat AMR.
Say Yong is a Senior Laboratory Technologist in Hadley’s group. With a B.Sc. from NTU’s School of Biological Sciences, he joined the group in 2020. Say Yong has contributed to several projects, including the differentiation of viral and bacterial infections, the measurement of COVID-19 neutralizing antibodies and detection of beta-lactamases. His research interests span diagnostic devices, virology, bacteriology, phages, mycobacteria, and parasites.